TY  - GEN
AU  - Brown,Philip M
AU  - Drossman,Douglas A
AU  - Wood,Alastair J J
AU  - Cline,Gary A
AU  - Frazier,Kenny S
AU  - Jackson,Jessica I
AU  - Bronner,Johanna
AU  - Freiman,Joel
AU  - Zambrowicz,Brian
AU  - Sands,Arthur
AU  - Gershon,Michael D
TI  - The tryptophan hydroxylase inhibitor LX1031 shows clinical benefit in patients with nonconstipating irritable bowel syndrome
SN  - 1528-0012
PY  - 2011///1013
KW  - Abdominal Pain
KW  - etiology
KW  - Adult
KW  - Biomarkers
KW  - urine
KW  - Biphenyl Compounds
KW  - administration & dosage
KW  - Constipation
KW  - Double-Blind Method
KW  - Feces
KW  - Female
KW  - Humans
KW  - Hydroxyindoleacetic Acid
KW  - Irritable Bowel Syndrome
KW  - complications
KW  - Male
KW  - Middle Aged
KW  - Pain Measurement
KW  - Phenylalanine
KW  - Serotonin
KW  - biosynthesis
KW  - Severity of Illness Index
KW  - Tryptophan Hydroxylase
KW  - antagonists & inhibitors
N1  - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1053/j.gastro.2011.05.005
ER  -