TY - GEN AU - Kelley,Joshua B AU - Datta,Sutirtha AU - Snow,Chelsi J AU - Chatterjee,Mandovi AU - Ni,Li AU - Spencer,Adam AU - Yang,Chun-Song AU - CubeƱas-Potts,Caelin AU - Matunis,Michael J AU - Paschal,Bryce M TI - The defective nuclear lamina in Hutchinson-gilford progeria syndrome disrupts the nucleocytoplasmic Ran gradient and inhibits nuclear localization of Ubc9 SN - 1098-5549 PY - 2011///1107 KW - Active Transport, Cell Nucleus KW - Cell Cycle Proteins KW - Guanine Nucleotide Exchange Factors KW - Humans KW - Nuclear Lamina KW - pathology KW - Nuclear Proteins KW - Progeria KW - metabolism KW - Sumoylation KW - Ubiquitin-Conjugating Enzymes KW - antagonists & inhibitors KW - ran GTP-Binding Protein KW - Ubiquitin-Conjugating Enzyme UBC9 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1128/MCB.05087-11 ER -