TY - GEN AU - Bielen,Aleksandra AU - Perryman,Lara AU - Box,Gary M AU - Valenti,Melanie AU - de Haven Brandon,Alexis AU - Martins,Vanessa AU - Jury,Alexa AU - Popov,Sergey AU - Gowan,Sharon AU - Jeay,Sebastien AU - Raynaud,Florence I AU - Hofmann,Francesco AU - Hargrave,Darren AU - Eccles,Suzanne A AU - Jones,Chris TI - Enhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β SN - 1538-8514 PY - 2011///1219 KW - Animals KW - Antineoplastic Agents KW - chemistry KW - Autophagy KW - drug effects KW - Cell Line, Tumor KW - Child KW - Female KW - Gene Expression Profiling KW - Gene Expression Regulation, Neoplastic KW - Glioblastoma KW - genetics KW - Humans KW - Mice KW - Mice, Nude KW - Neoplasm Staging KW - Phosphatidylinositol 3-Kinases KW - metabolism KW - Pyrimidines KW - Pyrroles KW - Receptor, IGF Type 1 KW - antagonists & inhibitors KW - Receptor, Platelet-Derived Growth Factor alpha KW - Receptor, Platelet-Derived Growth Factor beta KW - Signal Transduction KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1535-7163.MCT-11-0205 ER -