Bielen, Aleksandra

Enhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β. [electronic resource] - Molecular cancer therapeutics Aug 2011 - 1407-18 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1538-8514

10.1158/1535-7163.MCT-11-0205 doi


Animals
Antineoplastic Agents--chemistry
Autophagy--drug effects
Cell Line, Tumor
Child
Female
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Glioblastoma--genetics
Humans
Mice
Mice, Nude
Neoplasm Staging
Phosphatidylinositol 3-Kinases--metabolism
Pyrimidines--chemistry
Pyrroles--chemistry
Receptor, IGF Type 1--antagonists & inhibitors
Receptor, Platelet-Derived Growth Factor alpha--antagonists & inhibitors
Receptor, Platelet-Derived Growth Factor beta--antagonists & inhibitors
Signal Transduction--drug effects
Xenograft Model Antitumor Assays