Willis, Melanie Neely

Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunits. [electronic resource] - Biochemistry Jul 2011 - 6508-17 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1520-4995

10.1021/bi200708w doi


Animals
Catalytic Domain
Enzyme Stability
Glutamate-Cysteine Ligase--chemistry
Glutathione--biosynthesis
Homozygote
Humans
Kinetics
Mice
Models, Biological
Mutant Proteins--metabolism
Mutation--genetics
Protein Binding
Protein Structure, Secondary
Recombinant Proteins--metabolism
Saccharomyces cerevisiae--metabolism
Structural Homology, Protein
Temperature