Mayes, Patrick A <br/><br/>
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.  [electronic resource] 

 -  Cancer research  Aug 2011 
 - 5265-75 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-7445 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.CAN-11-1383  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenocarcinoma--blood supply<br/>Angiogenesis Inhibitors--pharmacology<br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>CDC2 Protein Kinase--antagonists & inhibitors<br/>Camptothecin--analogs & derivatives<br/>Cell Hypoxia--drug effects<br/>Cell Line, Tumor--drug effects<br/>Colonic Neoplasms--blood supply<br/>Drug Synergism<br/>Fluorouracil--pharmacology<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Glycogen Synthase Kinase 3--antagonists & inhibitors<br/>Glycogen Synthase Kinase 3 beta<br/>Humans<br/>Hypoxia-Inducible Factor 1, alpha Subunit--antagonists & inhibitors<br/>Inhibitor of Apoptosis Proteins--physiology<br/>Irinotecan<br/>Mice<br/>Mice, Nude<br/>Neoplasm Proteins--antagonists & inhibitors<br/>Protein Kinase Inhibitors--pharmacology<br/>Proto-Oncogene Proteins c-myb--physiology<br/>Pyrimidines--pharmacology<br/>RNA, Small Interfering--pharmacology<br/>Recombinant Proteins--pharmacology<br/>TNF-Related Apoptosis-Inducing Ligand--pharmacology<br/>Thiazoles--pharmacology<br/>Tumor Suppressor Protein p53--physiology<br/>Xenograft Model Antitumor Assays