TY  - GEN
AU  - Chou,Hsin-Hung
AU  - Chiu,Hsuan-Chao
AU  - Delaney,Nigel F
AU  - Segrè,Daniel
AU  - Marx,Christopher J
TI  - Diminishing returns epistasis among beneficial mutations decelerates adaptation
SN  - 1095-9203
PY  - 2011///0621
KW  - Adaptation, Physiological
KW  - Alleles
KW  - Biological Evolution
KW  - Epistasis, Genetic
KW  - Evolution, Molecular
KW  - Genes, Bacterial
KW  - Genetic Fitness
KW  - Genome, Bacterial
KW  - Glutathione
KW  - metabolism
KW  - Metabolic Networks and Pathways
KW  - genetics
KW  - Methylobacterium extorquens
KW  - cytology
KW  - Models, Genetic
KW  - Mutation
KW  - Selection, Genetic
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1126/science.1203799
ER  -