Wang, Haishan <br/><br/>
Discovery of (2E)-3--N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profile.  [electronic resource] 

 -  Journal of medicinal chemistry  Jul 2011 
 - 4694-720 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm2003552  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Benzimidazoles--chemical synthesis<br/>Biological Availability<br/>Cell Line, Tumor<br/>Dogs<br/>Drug Screening Assays, Antitumor<br/>Female<br/>Histone Deacetylase 1--antagonists & inhibitors<br/>Histone Deacetylase Inhibitors--chemical synthesis<br/>Humans<br/>Isoenzymes--antagonists & inhibitors<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Nude<br/>Microsomes, Liver--metabolism<br/>Neoplasm Transplantation<br/>Quantitative Structure-Activity Relationship<br/>Rats<br/>Rats, Wistar<br/>Stereoisomerism