Strong negative feedback from Erk to Raf confers robustness to MAPK signalling. [electronic resource]
- Molecular systems biology May 2011
- 489 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1744-4292
10.1038/msb.2011.27 doi
Base Sequence Cell Line Cell Proliferation--drug effects Extracellular Signal-Regulated MAP Kinases--genetics Feedback, Physiological Gene Silencing Humans MAP Kinase Signaling System--physiology Mathematical Computing Models, Biological Molecular Sequence Data Mutation Phosphorylation--drug effects Protein Processing, Post-Translational--drug effects Proto-Oncogene Proteins c-raf--genetics RNA, Small Interfering--metabolism Transfection