TY  - GEN
AU  - Aurelio,Luigi
AU  - Christopoulos,Arthur
AU  - Flynn,Bernard L
AU  - Scammells,Peter J
AU  - Sexton,Patrick M
AU  - Valant,Celine
TI  - The synthesis and biological evaluation of 2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophenes as allosteric modulators of the A1 adenosine receptor
SN  - 1464-3405
PY  - 2011///1122
KW  - Allosteric Regulation
KW  - drug effects
KW  - Amines
KW  - chemical synthesis
KW  - Animals
KW  - CHO Cells
KW  - Cells, Cultured
KW  - Cricetinae
KW  - Cricetulus
KW  - Cyclization
KW  - Inhibitory Concentration 50
KW  - Molecular Structure
KW  - Receptor, Adenosine A1
KW  - metabolism
KW  - Structure-Activity Relationship
KW  - Thiophenes
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bmcl.2011.04.080
ER  -