The oncogenic role of NS5A of hepatitis C virus is mediated by up-regulation of survivin gene expression in the hepatocellular cell through p53 and NF-κB pathways. [electronic resource]
- Cell biology international Dec 2011
- 1225-32 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1095-8355
10.1042/CBI20110102 doi
Apoptosis Carcinoma, Hepatocellular--genetics Down-Regulation Gene Expression Hep G2 Cells Hepacivirus--physiology Humans Immunohistochemistry Inhibitor of Apoptosis Proteins--genetics Liver Neoplasms--genetics NF-kappa B--metabolism Nitric Oxide Synthase Type II--genetics Oncogenes--physiology Signal Transduction Transfection Tumor Suppressor Protein p53--genetics Up-Regulation Viral Nonstructural Proteins--metabolism