Sutherland, Tara E

Analyzing airway inflammation with chemical biology: dissection of acidic mammalian chitinase function with a selective drug-like inhibitor. [electronic resource] - Chemistry & biology May 2011 - 569-79 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-1301

10.1016/j.chembiol.2011.02.017 doi


Animals
Binding Sites
Binding, Competitive
Chitinases--antagonists & inhibitors
Computer Simulation
Disease Models, Animal
Enzyme Inhibitors--chemistry
Eosinophils--immunology
Female
Gene Expression Regulation
Mice
Mice, Inbred BALB C
Neutrophils--immunology
Pneumonia--drug therapy
Protein Structure, Tertiary
RNA Interference
RNA, Small Interfering--metabolism
Xanthines--chemistry