Rao, Jia

Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells. [electronic resource] - Journal of translational medicine May 2011 - 71 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1479-5876

10.1186/1479-5876-9-71 doi


Adolescent
Adult
Aged
Antigens, CD34--metabolism
Apoptosis--drug effects
Caspase 3--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Curcumin--pharmacology
Daunorubicin--pharmacology
Drug Resistance, Neoplasm--drug effects
Drug Synergism
Female
G1 Phase--drug effects
Gene Expression Regulation, Leukemic--drug effects
Humans
Leukemia, Myeloid, Acute--enzymology
Male
Membrane Potential, Mitochondrial--drug effects
Middle Aged
Poly(ADP-ribose) Polymerases--metabolism
Protein Processing, Post-Translational--drug effects
Proto-Oncogene Proteins c-bcl-2--genetics
RNA, Messenger--genetics
RNA, Small Interfering--metabolism
S Phase--drug effects