TY - GEN AU - Ahmed,A AU - Yang,J AU - Maya-Mendoza,A AU - Jackson,D A AU - Ashcroft,M TI - Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1 SN - 2041-4889 PY - 2011///0913 KW - Apoptosis KW - drug effects KW - Ataxia Telangiectasia KW - metabolism KW - Breast Neoplasms KW - genetics KW - Cell Cycle Proteins KW - Cell Line, Tumor KW - Checkpoint Kinase 1 KW - Colorectal Neoplasms KW - DNA Damage KW - DNA Replication KW - Female KW - Furans KW - pharmacology KW - Gene Knockdown Techniques KW - Histones KW - Humans KW - Hypoxia KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - antagonists & inhibitors KW - Osteosarcoma KW - Phosphorylation KW - Protein Kinase Inhibitors KW - Protein Kinases KW - biosynthesis KW - Replication Origin KW - S Phase KW - Signal Transduction KW - Transfection KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/cddis.2011.42 ER -