TY - GEN AU - Wuertz,Karin AU - Quero,Lilian AU - Sekiguchi,Miho AU - Klawitter,Marina AU - Nerlich,Andreas AU - Konno,Shin-ichi AU - Kikuchi,Shin-ichi AU - Boos,Norbert TI - The red wine polyphenol resveratrol shows promising potential for the treatment of nucleus pulposus-mediated pain in vitro and in vivo SN - 1528-1159 PY - 2012///0215 KW - Adult KW - Aged KW - Analgesics KW - pharmacology KW - Animals KW - Anti-Inflammatory Agents KW - Cells, Cultured KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Extracellular Signal-Regulated MAP Kinases KW - metabolism KW - Female KW - Gene Expression Regulation KW - drug effects KW - Humans KW - Inflammation Mediators KW - Interleukin-1beta KW - genetics KW - Interleukin-6 KW - Interleukin-8 KW - Intervertebral Disc KW - JNK Mitogen-Activated Protein Kinases KW - Male KW - Matrix Metalloproteinase 1 KW - Matrix Metalloproteinase 13 KW - Matrix Metalloproteinase 3 KW - Middle Aged KW - NF-kappa B KW - Pain KW - drug therapy KW - Pain Measurement KW - RNA, Messenger KW - Radiculopathy KW - complications KW - Rats KW - Rats, Sprague-Dawley KW - Resveratrol KW - Signal Transduction KW - Sirtuin 1 KW - Stilbenes KW - Time Factors KW - Toll-Like Receptor 2 KW - Wine KW - Young Adult KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1097/BRS.0b013e318221e655 ER -