TY - GEN AU - Wang,Jie AU - Chen,Ying AU - Yuan,Qingxin AU - Tang,Wei AU - Zhang,Xiaoping AU - Osei,Kwame TI - Control of precursor maturation and disposal is an early regulative mechanism in the normal insulin production of pancreatic β-cells SN - 1932-6203 PY - 2011///1128 KW - Animals KW - Diabetes Mellitus, Type 2 KW - metabolism KW - Endoplasmic Reticulum KW - Gene Expression Regulation KW - Humans KW - Inflammation KW - Insulin KW - biosynthesis KW - Insulin-Secreting Cells KW - Islets of Langerhans KW - cytology KW - Mice KW - Mutation KW - Oxidative Stress KW - Proinsulin KW - Protein Folding KW - Time Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0019446 ER -