Control of precursor maturation and disposal is an early regulative mechanism in the normal insulin production of pancreatic β-cells. [electronic resource]
- PloS one Apr 2011
- e19446 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0019446 doi
Animals Diabetes Mellitus, Type 2--metabolism Endoplasmic Reticulum--metabolism Gene Expression Regulation Humans Inflammation Insulin--biosynthesis Insulin-Secreting Cells--metabolism Islets of Langerhans--cytology Mice Mutation Oxidative Stress Proinsulin--metabolism Protein Folding Time Factors