CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration. [electronic resource]
- The British journal of ophthalmology Feb 2012
- 208-12 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1468-2079
10.1136/bjo.2010.193680 doi
Aged Aged, 80 and over Antibodies, Monoclonal, Humanized--administration & dosage Complement Factor H--genetics Female Fluorescein Angiography Genotype High-Temperature Requirement A Serine Peptidase 1 Humans Indocyanine Green Intravitreal Injections Male Pilot Projects Polymerase Chain Reaction Polymorphism, Single Nucleotide Promoter Regions, Genetic--genetics Ranibizumab Serine Endopeptidases--genetics Treatment Outcome Vascular Endothelial Growth Factor A--genetics Visual Acuity--physiology Wet Macular Degeneration--drug therapy