TY  - GEN
AU  - Muhammad,Khalid
AU  - Roll,Petra
AU  - Seibold,Thomas
AU  - Kleinert,Stefan
AU  - Einsele,Hermann
AU  - Dörner,Thomas
AU  - Tony,Hans-Peter
TI  - Impact of IL-6 receptor inhibition on human memory B cells in vivo: impaired somatic hypermutation in preswitch memory B cells and modulation of mutational targeting in memory B cells
SN  - 1468-2060
PY  - 2011///1118
KW  - Adult
KW  - Aged
KW  - Antibodies, Monoclonal, Humanized
KW  - pharmacology
KW  - Antirheumatic Agents
KW  - Arthritis, Rheumatoid
KW  - drug therapy
KW  - B-Lymphocyte Subsets
KW  - drug effects
KW  - Etanercept
KW  - Female
KW  - Gene Rearrangement, B-Lymphocyte
KW  - genetics
KW  - Humans
KW  - Immunoglobulin G
KW  - Immunoglobulin Variable Region
KW  - Immunologic Memory
KW  - Male
KW  - Middle Aged
KW  - Prospective Studies
KW  - Receptors, Interleukin-6
KW  - antagonists & inhibitors
KW  - Receptors, Tumor Necrosis Factor
KW  - therapeutic use
KW  - Somatic Hypermutation, Immunoglobulin
KW  - immunology
KW  - Tumor Necrosis Factor-alpha
N1  - Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1136/ard.2010.141325
ER  -