Bungay, Peter J <br/><br/>
Preclinical and clinical pharmacokinetics of PF-02413873, a nonsteroidal progesterone receptor antagonist.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Aug 2011 
 - 1396-405 p.  digital 
<br/><br/> Publication Type: Journal Article; Randomized Controlled Trial 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.110.037234  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Biotransformation<br/>Caco-2 Cells<br/>Chromatography, High Pressure Liquid<br/>Dogs<br/>Dose-Response Relationship, Drug<br/>Double-Blind Method<br/>Drug Evaluation, Preclinical<br/>Hepatocytes--enzymology<br/>Humans<br/>Injections, Intravenous<br/>Intestinal Secretions--chemistry<br/>Male<br/>Microsomes, Liver--enzymology<br/>Models, Biological<br/>Molecular Structure<br/>Predictive Value of Tests<br/>Prospective Studies<br/>Protein Binding<br/>Pyrazoles--blood<br/>Rats<br/>Rats, Sprague-Dawley<br/>Receptors, Progesterone--antagonists & inhibitors<br/>Solubility<br/>Species Specificity<br/>Sulfones--blood<br/>Tandem Mass Spectrometry