TY - GEN AU - Wang,Jinsong AU - Peng,Xinzhi AU - Lassance-Soares,Roberta M AU - Najafi,Amir H AU - Alderman,Lee O AU - Sood,Subeena AU - Xue,Zhenyi AU - Chan,Rosanna AU - Faber,James E AU - Epstein,Stephen E AU - Burnett,Mary Susan TI - Aging-induced collateral dysfunction: impaired responsiveness of collaterals and susceptibility to apoptosis via dysfunctional eNOS signaling SN - 1937-5395 PY - 2012///0312 KW - Age Factors KW - Aging KW - metabolism KW - Animals KW - Aorta KW - enzymology KW - Apoptosis KW - Arterial Occlusive Diseases KW - Blotting, Western KW - Bone Marrow Transplantation KW - Cell Movement KW - Cells, Cultured KW - Collateral Circulation KW - Cyclic Nucleotide Phosphodiesterases, Type 5 KW - Disease Models, Animal KW - Endothelial Cells KW - Female KW - Femoral Artery KW - surgery KW - Laser-Doppler Flowmetry KW - Ligation KW - Lower Extremity KW - blood supply KW - Mice KW - Mice, Inbred C57BL KW - Muscle, Smooth, Vascular KW - Myocytes, Smooth Muscle KW - Neovascularization, Physiologic KW - Nitric Oxide Synthase Type III KW - Perfusion Imaging KW - methods KW - Phosphorylation KW - Regional Blood Flow KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1007/s12265-011-9280-4 ER -