TY - GEN AU - Tsetsarkin,Konstantin A AU - Chen,Rubing AU - Leal,Grace AU - Forrester,Naomi AU - Higgs,Stephen AU - Huang,Jing AU - Weaver,Scott C TI - Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes SN - 1091-6490 PY - 2011///0715 KW - Adaptation, Physiological KW - Aedes KW - virology KW - Alphavirus Infections KW - epidemiology KW - Amino Acid Substitution KW - Animals KW - Asia, Southeastern KW - Base Sequence KW - Chikungunya Fever KW - Chikungunya virus KW - genetics KW - Communicable Diseases, Emerging KW - DNA, Viral KW - Epistasis, Genetic KW - Evolution, Molecular KW - Green Fluorescent Proteins KW - Humans KW - Insect Vectors KW - Mice KW - Models, Molecular KW - Phylogeny KW - Recombinant Fusion Proteins KW - Viral Envelope Proteins KW - chemistry N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1018344108 ER -