Wiley, Luke A

The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens. [electronic resource] - Disease models & mechanisms Jul 2011 - 484-95 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1754-8411

10.1242/dmm.006593 doi


Activin Receptors, Type I--metabolism
Aging--pathology
Animals
Apoptosis
Biomarkers--metabolism
Bone Morphogenetic Protein Receptors--metabolism
Cataract--prevention & control
Cell Cycle
Cell Differentiation
Cell Proliferation
Epithelial Cells--metabolism
Eye Neoplasms--metabolism
Humans
Lens, Crystalline--metabolism
Mice
Mice, Knockout
Models, Biological
Phosphorylation
Phosphoserine--metabolism
Posterior Capsule of the Lens--metabolism
Tumor Suppressor Protein p53--genetics