Pinto, Orlando

Synthesis of tetrahydronaphthalene lignan esters by intramolecular cyclization of ethyl p-azidophenyl-2-phenylalkanoates and evaluation of the growth inhibition of human tumor cell lines. [electronic resource] - Journal of medicinal chemistry May 2011 - 3175-87 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm101182s doi


Antineoplastic Agents--chemical synthesis
Azides--chemical synthesis
Cell Line, Tumor
Cell Proliferation--drug effects
Crystallography, X-Ray
Cyclization
Drug Screening Assays, Antitumor
Esters
Humans
Lignans--chemical synthesis
Models, Molecular
Spiro Compounds--chemical synthesis
Structure-Activity Relationship
Tetrahydronaphthalenes--chemical synthesis