TY - GEN AU - Upadhayaya,RamShankar AU - Deshpande,Sachin Gangadhar AU - Li,Qing AU - Kardile,Ramakant Asaram AU - Sayyed,Aftab Yusuf AU - Kshirsagar,Eknath Kamalakar AU - Salunke,Rahul Vilas AU - Dixit,Shailesh Satish AU - Zhou,Chuanzheng AU - Földesi,András AU - Chattopadhyaya,Jyoti TI - Carba-LNA-5MeC/A/G/T modified oligos show nucleobase-specific modulation of 3'-exonuclease activity, thermodynamic stability, RNA selectivity, and RNase H elicitation: synthesis and biochemistry SN - 1520-6904 PY - 2011///0920 KW - Base Sequence KW - Cyclization KW - Enzyme Stability KW - Escherichia coli KW - enzymology KW - Exonucleases KW - metabolism KW - Humans KW - Models, Molecular KW - Molecular Conformation KW - Nucleic Acid Denaturation KW - Nucleic Acid Hybridization KW - Oligonucleotides KW - chemistry KW - Oligonucleotides, Antisense KW - blood KW - Organophosphorus Compounds KW - RNA KW - Ribonuclease H KW - Substrate Specificity KW - Thermodynamics KW - Transition Temperature N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/jo200073q ER -