TY - GEN AU - Winer,Daniel A AU - Winer,Shawn AU - Shen,Lei AU - Wadia,Persis P AU - Yantha,Jason AU - Paltser,Geoffrey AU - Tsui,Hubert AU - Wu,Ping AU - Davidson,Matthew G AU - Alonso,Michael N AU - Leong,Hwei X AU - Glassford,Alec AU - Caimol,Maria AU - Kenkel,Justin A AU - Tedder,Thomas F AU - McLaughlin,Tracey AU - Miklos,David B AU - Dosch,H-Michael AU - Engleman,Edgar G TI - B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies SN - 1546-170X PY - 2011///0705 KW - Animals KW - Autoantibodies KW - biosynthesis KW - Autoantigens KW - immunology KW - Autoimmunity KW - B-Lymphocytes KW - Dietary Fats KW - adverse effects KW - Glucose KW - metabolism KW - Humans KW - Immunoglobulin G KW - Immunoglobulin mu-Chains KW - genetics KW - Inflammation KW - Insulin Resistance KW - Intra-Abdominal Fat KW - Lymphocyte Activation KW - Lymphocyte Depletion KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Obesity KW - etiology KW - T-Lymphocytes N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nm.2353 ER -