TY - GEN AU - Lindberg,Karolina AU - Helguero,Luisa A AU - Omoto,Yoko AU - Gustafsson,Jan-Åke AU - Haldosén,Lars-Arne TI - Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity SN - 1465-542X PY - 2012///0525 KW - Antineoplastic Agents, Hormonal KW - pharmacology KW - Biomarkers, Tumor KW - Breast Neoplasms KW - drug therapy KW - Cell Line, Tumor KW - Cell Proliferation KW - Class I Phosphatidylinositol 3-Kinases KW - Down-Regulation KW - Drug Resistance, Neoplasm KW - genetics KW - Estrogen Receptor beta KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Neuregulin-1 KW - metabolism KW - PTEN Phosphohydrolase KW - Phosphatidylinositol 3-Kinases KW - Proto-Oncogene Mas KW - Proto-Oncogene Proteins c-akt KW - Receptor, ErbB-2 KW - Receptor, ErbB-3 KW - Signal Transduction KW - Tamoxifen KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/bcr2865 ER -