TY  - GEN
AU  - Gogia,Spriha
AU  - Balaram,Hemalatha
AU  - Puranik,Mrinalini
TI  - Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate
SN  - 1520-4995
PY  - 2011///0801
KW  - Animals
KW  - Catalytic Domain
KW  - genetics
KW  - Deuterium Exchange Measurement
KW  - Guanosine Monophosphate
KW  - chemistry
KW  - Humans
KW  - Hydrogen-Ion Concentration
KW  - Hypoxanthine Phosphoribosyltransferase
KW  - Inosine Monophosphate
KW  - Plasmodium falciparum
KW  - enzymology
KW  - Protein Binding
KW  - Purine Nucleotides
KW  - Ribonucleotides
KW  - Spectrum Analysis, Raman
KW  - Substrate Specificity
KW  - Toxoplasma
KW  - Xanthine
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/bi102039b
ER  -