Gogia, Spriha

Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate. [electronic resource] - Biochemistry May 2011 - 4184-93 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1520-4995

10.1021/bi102039b doi


Animals
Catalytic Domain--genetics
Deuterium Exchange Measurement
Guanosine Monophosphate--chemistry
Humans
Hydrogen-Ion Concentration
Hypoxanthine Phosphoribosyltransferase--chemistry
Inosine Monophosphate--chemistry
Plasmodium falciparum--enzymology
Protein Binding--genetics
Purine Nucleotides--chemistry
Ribonucleotides--chemistry
Spectrum Analysis, Raman
Substrate Specificity--genetics
Toxoplasma--enzymology
Xanthine