TY - GEN AU - Kurita,Satoshi AU - Mott,Justin L AU - Cazanave,Sophie C AU - Fingas,Christian D AU - Guicciardi,Maria E AU - Bronk,Steve F AU - Roberts,Lewis R AU - Fernandez-Zapico,Martin E AU - Gores,Gregory J TI - Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells SN - 1932-6203 PY - 2011///0825 KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - genetics KW - BH3 Interacting Domain Death Agonist Protein KW - Bcl-2-Like Protein 11 KW - Cell Line KW - Cell Line, Tumor KW - Chromatin Immunoprecipitation KW - Electrophoretic Mobility Shift Assay KW - Hedgehog Proteins KW - Humans KW - Immunoblotting KW - Inhibitor of Apoptosis Proteins KW - Kruppel-Like Transcription Factors KW - Membrane Proteins KW - Nuclear Proteins KW - Promoter Regions, Genetic KW - Proto-Oncogene Proteins KW - RNA Interference KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - TNF-Related Apoptosis-Inducing Ligand KW - pharmacology KW - Transcription Factors KW - Veratrum Alkaloids KW - X-Linked Inhibitor of Apoptosis Protein KW - Zinc Finger Protein GLI1 KW - Zinc Finger Protein Gli2 KW - bcl-2 Homologous Antagonist-Killer Protein KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0018330 ER -