TY - GEN AU - Guo,Jianhui AU - Zheng,Li AU - Liu,Wenyong AU - Wang,Xianshu AU - Wang,Zemin AU - Wang,Zehua AU - French,Amy J AU - Kang,Dongchon AU - Chen,Lin AU - Thibodeau,Stephen N AU - Liu,Wanguo TI - Frequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer SN - 1538-7445 PY - 2011///0715 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Base Sequence KW - Cell Line, Tumor KW - Cisplatin KW - Colorectal Neoplasms KW - drug therapy KW - Cytochromes b KW - genetics KW - DNA, Mitochondrial KW - DNA-Binding Proteins KW - Down-Regulation KW - Frameshift Mutation KW - HCT116 Cells KW - Humans KW - Mice KW - Mice, Nude KW - Microsatellite Instability KW - Mitochondrial Proteins KW - Transcription Factors KW - Transcription, Genetic KW - Transplantation, Heterologous N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-10-3482 ER -