Raval, Preeti

Revisiting glitazars: thiophene substituted oxazole containing α-ethoxy phenylpropanoic acid derivatives as highly potent PPARα/γ dual agonists devoid of adverse effects in rodents. [electronic resource] - Bioorganic & medicinal chemistry letters May 2011 - 3103-9 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2011.03.020 doi


Administration, Oral
Animals
Cell Line
Dose-Response Relationship, Drug
Hypoglycemic Agents--chemical synthesis
Inhibitory Concentration 50
Mice
Molecular Structure
Oxazoles--chemistry
PPAR alpha--agonists
PPAR gamma--agonists
Phenylpropionates--chemical synthesis
Protein Binding--drug effects
Rats
Rats, Wistar
Rosiglitazone
Thiazolidinediones--chemical synthesis
Thiophenes--chemistry