Foti, Robert S <br/><br/>
Mechanism-based inactivation of cytochrome P450 3A4 by mibefradil through heme destruction.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Jul 2011 
 - 1188-95 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.111.038505  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Chromatography, High Pressure Liquid<br/>Cytochrome P-450 CYP3A<br/>Cytochrome P-450 CYP3A Inhibitors<br/>Enzyme Inhibitors--pharmacology<br/>Heme--metabolism<br/>Humans<br/>Hydrolysis<br/>Mass Spectrometry<br/>Mibefradil--pharmacology<br/>Spectrophotometry, Ultraviolet