Liu, Xiaodan

Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes. [electronic resource] - Chemical research in toxicology May 2011 - 726-36 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1520-5010

10.1021/tx2000152 doi


Agaricales--chemistry
Alkylation
Antineoplastic Agents--pharmacology
Antioxidants--metabolism
Cell Survival--drug effects
Cysteine--metabolism
Enzyme Inhibitors--pharmacology
Glutathione Peroxidase--antagonists & inhibitors
HeLa Cells
Humans
Neoplasms--drug therapy
Polycyclic Sesquiterpenes
Selenocysteine--metabolism
Sesquiterpenes--pharmacology
Spiro Compounds--pharmacology
Thioredoxin-Disulfide Reductase--antagonists & inhibitors