TY  - GEN
AU  - Radi,Marco
AU  - Dreassi,Elena
AU  - Brullo,Chiara
AU  - Crespan,Emmanuele
AU  - Tintori,Cristina
AU  - Bernardo,Vincenzo
AU  - Valoti,Massimo
AU  - Zamperini,Claudio
AU  - Daigl,Henry
AU  - Musumeci,Francesca
AU  - Carraro,Fabio
AU  - Naldini,Antonella
AU  - Filippi,Irene
AU  - Maga,Giovanni
AU  - Schenone,Silvia
AU  - Botta,Maurizio
TI  - Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study
SN  - 1520-4804
PY  - 2011///0704
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Cell Hypoxia
KW  - Cell Line, Tumor
KW  - Drug Screening Assays, Antitumor
KW  - Humans
KW  - Leukemia
KW  - pathology
KW  - Magnetic Resonance Spectroscopy
KW  - Mass Spectrometry
KW  - Models, Molecular
KW  - Pyrazoles
KW  - Pyrimidines
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm1012819
ER  -