Radi, Marco <br/><br/>
Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.  [electronic resource] 

 -  Journal of medicinal chemistry  Apr 2011 
 - 2610-26 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm1012819  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Cell Hypoxia<br/>Cell Line, Tumor<br/>Drug Screening Assays, Antitumor<br/>Humans<br/>Leukemia--pathology<br/>Magnetic Resonance Spectroscopy<br/>Mass Spectrometry<br/>Models, Molecular<br/>Pyrazoles--chemical synthesis<br/>Pyrimidines--chemical synthesis