TY  - GEN
AU  - Hoffmann,Hans-Heinrich
AU  - Kunz,Andrea
AU  - Simon,Viviana A
AU  - Palese,Peter
AU  - Shaw,Megan L
TI  - Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis
SN  - 1091-6490
PY  - 2011///0701
KW  - Animals
KW  - Antiviral Agents
KW  - pharmacology
KW  - Autoradiography
KW  - Carbamates
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - drug effects
KW  - Chickens
KW  - DNA Primers
KW  - genetics
KW  - Dihydroorotate Dehydrogenase
KW  - Furans
KW  - Humans
KW  - Indoles
KW  - Lamivudine
KW  - Mammals
KW  - Nevirapine
KW  - Oxadiazoles
KW  - Oxidoreductases Acting on CH-CH Group Donors
KW  - metabolism
KW  - Pyrimidines
KW  - biosynthesis
KW  - Pyrrolidinones
KW  - Raltegravir Potassium
KW  - Species Specificity
KW  - Sulfonamides
KW  - Time Factors
KW  - Virus Replication
KW  - Viruses
KW  - beta-Galactosidase
N1  - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.1101143108
ER  -