Hoffmann, Hans-Heinrich <br/><br/>
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  Apr 2011 
 - 5777-82 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1101143108  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antiviral Agents--pharmacology<br/>Autoradiography<br/>Carbamates<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Chickens<br/>DNA Primers--genetics<br/>Dihydroorotate Dehydrogenase<br/>Furans<br/>Humans<br/>Indoles--pharmacology<br/>Lamivudine<br/>Mammals<br/>Nevirapine<br/>Oxadiazoles--pharmacology<br/>Oxidoreductases Acting on CH-CH Group Donors--metabolism<br/>Pyrimidines--biosynthesis<br/>Pyrrolidinones<br/>Raltegravir Potassium<br/>Species Specificity<br/>Sulfonamides<br/>Time Factors<br/>Virus Replication--drug effects<br/>Viruses--drug effects<br/>beta-Galactosidase--metabolism