Nesterovitch, Andrew B

Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans. [electronic resource] - The American journal of pathology Apr 2011 - 1701-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1525-2191

10.1016/j.ajpath.2010.12.053 doi


Adrenal Cortex Hormones--pharmacology
Animals
Autoantibodies--chemistry
Chromosome Mapping
Hereditary Autoinflammatory Diseases--genetics
Homozygote
Humans
Immunoglobulins--chemistry
Inflammation
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mutation
Neutrophils--metabolism
Protein Tyrosine Phosphatase, Non-Receptor Type 6--genetics
Skin Diseases--metabolism