TY  - GEN
AU  - Pirotte,Bernard
AU  - de Tullio,Pascal
AU  - Boverie,Stéphane
AU  - Michaux,Catherine
AU  - Lebrun,Philippe
TI  - Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channels
SN  - 1520-4804
PY  - 2011///0801
KW  - Animals
KW  - Aorta
KW  - drug effects
KW  - Benzothiadiazines
KW  - chemical synthesis
KW  - Diazoxide
KW  - analogs & derivatives
KW  - Female
KW  - Hydrogen Bonding
KW  - Hydrogen-Ion Concentration
KW  - In Vitro Techniques
KW  - Insulin
KW  - metabolism
KW  - Insulin Secretion
KW  - Insulin-Secreting Cells
KW  - Ion Channel Gating
KW  - KATP Channels
KW  - physiology
KW  - Models, Molecular
KW  - Molecular Conformation
KW  - Muscle Contraction
KW  - Muscle Relaxation
KW  - Muscle, Smooth
KW  - Rats
KW  - Rats, Wistar
KW  - Stereoisomerism
KW  - Structure-Activity Relationship
KW  - Uterus
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm200100c
ER  -