Pirotte, Bernard <br/><br/>
Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channels.  [electronic resource] 

 -  Journal of medicinal chemistry  May 2011 
 - 3188-99 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm200100c  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Aorta--drug effects<br/>Benzothiadiazines--chemical synthesis<br/>Diazoxide--analogs & derivatives<br/>Female<br/>Hydrogen Bonding<br/>Hydrogen-Ion Concentration<br/>In Vitro Techniques<br/>Insulin--metabolism<br/>Insulin Secretion<br/>Insulin-Secreting Cells--drug effects<br/>Ion Channel Gating<br/>KATP Channels--physiology<br/>Models, Molecular<br/>Molecular Conformation<br/>Muscle Contraction--drug effects<br/>Muscle Relaxation--drug effects<br/>Muscle, Smooth--drug effects<br/>Rats<br/>Rats, Wistar<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>Uterus--drug effects