TY - GEN AU - Jung,Carole AU - Gené,Gemma G AU - Tomás,Marta AU - Plata,Cristina AU - Selent,Jana AU - Pastor,Manuel AU - Fandos,César AU - Senti,Mariano AU - Lucas,Gavin AU - Elosua,Roberto AU - Valverde,Miguel A TI - A gain-of-function SNP in TRPC4 cation channel protects against myocardial infarction SN - 1755-3245 PY - 2011///1123 KW - Adult KW - Aged KW - Analysis of Variance KW - Animals KW - CHO Cells KW - Calcium Signaling KW - Case-Control Studies KW - Chi-Square Distribution KW - Cricetinae KW - Cricetulus KW - Diabetes Complications KW - genetics KW - Exons KW - Female KW - Gene Frequency KW - Genetic Association Studies KW - Genotype KW - HEK293 Cells KW - Humans KW - Linkage Disequilibrium KW - Logistic Models KW - Male KW - Membrane Potentials KW - Middle Aged KW - Models, Molecular KW - Muscarinic Agonists KW - pharmacology KW - Mutagenesis, Site-Directed KW - Myocardial Infarction KW - Odds Ratio KW - Patch-Clamp Techniques KW - Phenotype KW - Phosphorylation KW - Polymorphism, Single Nucleotide KW - Protein Conformation KW - Risk Assessment KW - Risk Factors KW - Spain KW - Structure-Activity Relationship KW - TRPC Cation Channels KW - chemistry KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/cvr/cvr083 ER -