TY - GEN AU - Nogueira,L AU - Ruiz-Ontañon,P AU - Vazquez-Barquero,A AU - Lafarga,M AU - Berciano,M T AU - Aldaz,B AU - Grande,L AU - Casafont,I AU - Segura,V AU - Robles,E F AU - Suarez,D AU - Garcia,L F AU - Martinez-Climent,J A AU - Fernandez-Luna,J L TI - Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo SN - 1476-5594 PY - 2011///1025 KW - Animals KW - Blotting, Western KW - Carbazoles KW - pharmacology KW - Cell Differentiation KW - genetics KW - Cell Proliferation KW - drug effects KW - Cellular Senescence KW - Cyclin D1 KW - Female KW - Gene Expression Profiling KW - Glioblastoma KW - drug therapy KW - Glycosides KW - Humans KW - I-kappa B Kinase KW - antagonists & inhibitors KW - I-kappa B Proteins KW - Mice KW - Mice, Inbred BALB C KW - Mice, Knockout KW - NF-kappa B KW - Neural Stem Cells KW - Nitriles KW - Oligonucleotide Array Sequence Analysis KW - Protein Kinase Inhibitors KW - RNA Interference KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Sulfones KW - Tumor Cells, Cultured KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/onc.2011.74 ER -