Nogueira, L
Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo. [electronic resource]
- Oncogene Aug 2011
- 3537-48 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 1476-5594
Standard No.: 10.1038/onc.2011.74 doi
Subjects--Topical Terms: Animals Blotting, Western Carbazoles--pharmacology Cell Differentiation--genetics Cell Proliferation--drug effects Cellular Senescence--drug effects Cyclin D1--genetics Female Gene Expression Profiling Glioblastoma--drug therapy Glycosides--pharmacology Humans I-kappa B Kinase--antagonists & inhibitors I-kappa B Proteins--genetics Mice Mice, Inbred BALB C Mice, Knockout NF-kappa B--antagonists & inhibitors Neural Stem Cells--drug effects Nitriles--pharmacology Oligonucleotide Array Sequence Analysis Protein Kinase Inhibitors--pharmacology RNA Interference Reverse Transcriptase Polymerase Chain Reaction Signal Transduction--drug effects Sulfones--pharmacology Tumor Cells, Cultured Xenograft Model Antitumor Assays