Nogueira, L

Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo. [electronic resource] - Oncogene Aug 2011 - 3537-48 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-5594

10.1038/onc.2011.74 doi


Animals
Blotting, Western
Carbazoles--pharmacology
Cell Differentiation--genetics
Cell Proliferation--drug effects
Cellular Senescence--drug effects
Cyclin D1--genetics
Female
Gene Expression Profiling
Glioblastoma--drug therapy
Glycosides--pharmacology
Humans
I-kappa B Kinase--antagonists & inhibitors
I-kappa B Proteins--genetics
Mice
Mice, Inbred BALB C
Mice, Knockout
NF-kappa B--antagonists & inhibitors
Neural Stem Cells--drug effects
Nitriles--pharmacology
Oligonucleotide Array Sequence Analysis
Protein Kinase Inhibitors--pharmacology
RNA Interference
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects
Sulfones--pharmacology
Tumor Cells, Cultured
Xenograft Model Antitumor Assays