Lucas, Carrie L

LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L. [electronic resource] - Blood May 2011 - 5532-40 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1528-0020

10.1182/blood-2010-11-318675 doi


Adoptive Transfer
Animals
Antigens, CD--genetics
Antigens, Surface--genetics
Apoptosis Regulatory Proteins--deficiency
B7-1 Antigen--genetics
B7-H1 Antigen
Bone Marrow Transplantation--immunology
CD4-Positive T-Lymphocytes--immunology
CD40 Ligand--antagonists & inhibitors
CD8-Positive T-Lymphocytes--immunology
CTLA-4 Antigen
Female
Immune Tolerance
Membrane Glycoproteins--deficiency
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Models, Immunological
Peptides--deficiency
Programmed Cell Death 1 Ligand 2 Protein
Programmed Cell Death 1 Receptor
Signal Transduction--immunology
Transforming Growth Factor beta--immunology
Transplantation, Homologous
Lymphocyte Activation Gene 3 Protein