Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity. [electronic resource]
- Cardiovascular research May 2011
- 353-63 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1755-3245
10.1093/cvr/cvq410 doi
Animals Aorta--cytology Cattle Caveolae--metabolism Cells, Cultured Coronary Vessels--cytology Cyclic GMP-Dependent Protein Kinase Type I Cyclic GMP-Dependent Protein Kinases--genetics Cyclic Nucleotide Phosphodiesterases, Type 5--genetics Endothelial Cells--cytology Humans Hypertension, Pulmonary--metabolism Membrane Microdomains--metabolism Mice Nitric Oxide Synthase Type III--metabolism Pulmonary Artery--cytology Signal Transduction--physiology Umbilical Veins--cytology Vasodilation--physiology