TY  - GEN
AU  - Xie,Fang
AU  - Zhou,Xin
AU  - Genter,Mary Beth
AU  - Behr,Melissa
AU  - Gu,Jun
AU  - Ding,Xinxin
TI  - The tissue-specific toxicity of methimazole in the mouse olfactory mucosa is partly mediated through target-tissue metabolic activation by CYP2A5
SN  - 1521-009X
PY  - 2011///0912
KW  - Animals
KW  - Antithyroid Agents
KW  - pharmacokinetics
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Cytochrome P-450 CYP2A6
KW  - Cytochrome P450 Family 2
KW  - Liver
KW  - drug effects
KW  - Metabolic Clearance Rate
KW  - Methimazole
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - NADPH-Ferrihemoprotein Reductase
KW  - Olfactory Mucosa
KW  - Organ Specificity
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1124/dmd.110.037895
ER  -