Renard, Brice-Loïc <br/><br/>
An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors.  [electronic resource] 

 -  European journal of medicinal chemistry  May 2011 
 - 1935-41 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2011.02.037  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>CHO Cells<br/>Chemistry, Physical<br/>Cricetinae<br/>Cricetulus<br/>Cystic Fibrosis Transmembrane Conductance Regulator--antagonists & inhibitors<br/>Drug Discovery<br/>Molecular Conformation<br/>Ornithine--analogs & derivatives<br/>Pyrimidines--chemical synthesis<br/>Pyruvaldehyde--analogs & derivatives<br/>Stereoisomerism<br/>Structure-Activity Relationship