TY - GEN AU - Dong,Jianying AU - Sereno,Arlene AU - Aivazian,Dikran AU - Langley,Emma AU - Miller,Brian R AU - Snyder,William B AU - Chan,Eric AU - Cantele,Matt AU - Morena,Ronald AU - Joseph,Ingrid B J K AU - Boccia,Antonio AU - Virata,Cyrus AU - Gamez,James AU - Yco,Grace AU - Favis,Michael AU - Wu,Xiufeng AU - Graff,Christilyn P AU - Wang,Qin AU - Rohde,Ellen AU - Rennard,Rachel AU - Berquist,Lisa AU - Huang,Flora AU - Zhang,Ying AU - Gao,Sharon X AU - Ho,Steffan N AU - Demarest,Stephen J AU - Reff,Mitchell E AU - Hariharan,Kandasamy AU - Glaser,Scott M TI - A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity SN - 1942-0870 PY - 2011///1227 KW - Animals KW - Antibodies, Bispecific KW - immunology KW - Antibodies, Monoclonal KW - Antibody Affinity KW - Antibody Specificity KW - Blotting, Western KW - CHO Cells KW - Cell Line, Tumor KW - Cell Survival KW - drug effects KW - Cricetinae KW - Cricetulus KW - Dose-Response Relationship, Drug KW - ErbB Receptors KW - Humans KW - Immunoglobulin G KW - Mice KW - Mice, Nude KW - Mice, SCID KW - Neoplasms KW - drug therapy KW - Phosphorylation KW - Receptor, IGF Type 1 KW - Signal Transduction KW - Single-Chain Antibodies KW - Tumor Burden KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.4161/mabs.3.3.15188 ER -