Dong, Jianying <br/><br/>
A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity.  [electronic resource] 

 -  mAbs   
 - 273-88 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1942-0870 
<br/><br/><label>Standard No.: </label>10.4161/mabs.3.3.15188  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Bispecific--immunology<br/>Antibodies, Monoclonal--immunology<br/>Antibody Affinity--immunology<br/>Antibody Specificity--immunology<br/>Blotting, Western<br/>CHO Cells<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Cricetinae<br/>Cricetulus<br/>Dose-Response Relationship, Drug<br/>ErbB Receptors--immunology<br/>Humans<br/>Immunoglobulin G--immunology<br/>Mice<br/>Mice, Nude<br/>Mice, SCID<br/>Neoplasms--drug therapy<br/>Phosphorylation--drug effects<br/>Receptor, IGF Type 1--immunology<br/>Signal Transduction--drug effects<br/>Single-Chain Antibodies--immunology<br/>Tumor Burden--drug effects<br/>Xenograft Model Antitumor Assays